We have 4yo and 7yo, and we always drive to WDW with them. We've stayed all over the place, including last spring break at Jambo. We bused over to AK, but drove to the other parks. Easy peasy. Parking at Jambo isn't too bad, though sometimes it's a bit of a hike to the car.
We typically rope drop, and go back to the hotel for an afternoon nap/pool time. I mean, we'll use the monorail or boat or something if we stay at
DVC resorts with those options, but we will usually opt for driving over buses. Just easier, more flexible, can come and go when we like. At least if we're walking to the car it feels like progress, rather than twiddling our thumbs waiting for buses. We still take a (double) stroller, so if I'm gonna fold that, I might as well be putting it in the car rather than dealing with the bus. Maybe your kid has aged out of that, though.
I don't think we've done
MNSSHP with the kids, so I'm not sure what that's like by car. I've not done car rental pickup/return at MCO so I don't know what that's like, but depending on the time of your flight, maybe driving gives you an option to hit a few other things (Disney Springs?) on your way over to the airport that you otherwise wouldn't.
Good luck with your decision!