The Vaccine Discussion Thread

[Intr3pid]

So, J&J is actually conducting a two-dose trial in parallel. Known as ENSEMBLE 2, it was launched in November and would involve up to 30,000 participants.

https://www.jnj.com/johnson-johnson...nterim-analysis-of-its-phase-3-ensemble-trial
It's not clear whether these are new participants or the single-dose participants being given a second dose. The single-dose trial was launched in September two months before the double-dose launch. It means we might get the double-dose results in March - and if the company just began a reformulated vaccine study, the results from that study by early summer.

More data at hand from the single-dose trial results:
https://www.jnj.com/johnson-johnson...nterim-analysis-of-its-phase-3-ensemble-trial
It looks like the South African cases comprised about 15% of the total. I don't know if it's coincidental, but they did report 15% incidence of the severe cases overall.

 

[sethschroeder]

Downside is that with J&J if its less effective about making you "immune" then it means more infections for possible mutation to occur.

I know everyone wants to eradicate severe instances of exposure but I am just thinking long term because to me that is the bigger issue at this point since we do have working vaccines of multiple variations now.

 

[ruadisneyfan2]

I got my 2nd Pfizer shot today.
Feeling fine at the moment but getting laundry done early because I expect to feel like crap for most of the weekend.

 

[nycdisneygal]

I will get my 2nd dose MOderna tuesday. Then I have to work 12 hours the next time. Hoping I dont feel ill....Losing hope that my august cruise will happen...

 

[n2mm]

I got my 2nd Pfizer shot today.
Feeling fine at the moment but getting laundry done early because I expect to feel like crap for most of the weekend.

getting my #2 on feb 11th. How did you do? I got no reaction for Pfizer #1? I ALWAYS get shots in my dominant arm. moving your arm is key. This has worked out for me. I’ve gotten flu shots and most recently my pneumonia shot in December and my #1 pfizer shot all in my right arm and so far I don’t even get a sore arm except at night slightly, so I do take a Tylenol before bed.

 

[ruadisneyfan2]

getting my #2 on feb 11th. How did you do? I got no reaction for Pfizer #1? I ALWAYS get shots in my dominant arm. moving your arm is key. This has worked out for me. I’ve gotten flu shots and most recently my pneumonia shot in December and my #1 pfizer shot all in my right arm and so far I don’t even get a sore arm except at night slightly, so I do take a Tylenol before bed.

So far just feeling mild fatigue. All my itchy spots that were almost gone from shot #1 have been reawakened. Not terribly but I notice I am scratching a lot in those areas. I've never had anything but a sore spot on my arm for past vaccines. While waiting the 15 mins post injection, I massaged the area. I didn't do that the first time and my arm is not sore this time.
The itchy rash that I had last time didn't begin until 4 days later so I know I'm not out of the woods yet.

 

[Chuck S]

So far just feeling mild fatigue. All my itchy spots that were almost gone from shot #1 have been reawakened. Not terribly but I notice I am scratching a lot in those areas. I've never had anything but a sore spot on my arm for past vaccines. While waiting the 15 mins post injection, I massaged the area. I didn't do that the first time and my arm is not sore this time.
The itchy rash that I had last time didn't begin until 4 days later so I know I'm not out of the woods yet.

Did you get Pfizer or Moderna?

 

[ruadisneyfan2]

Did you get Pfizer or Moderna?

Pfizer

 

[jlwhitney]

Downside is that with J&J if its less effective about making you "immune" then it means more infections for possible mutation to occur.

I know everyone wants to eradicate severe instances of exposure but I am just thinking long term because to me that is the bigger issue at this point since we do have working vaccines of multiple variations now.

They are too a point blowing the mutation thing out of proportion. It is a good thing and normal it is mutating. It is still mutating much slower than the flu. Plus pretty much no virus has mutated to cause a more severe disease. It's actually not beneficial for viruses to kill the host(person). In time its much more likely to mutate in causing a more mild disease and also expected by many viral researchers.

 

[AquaDame]

Sounds like the counties around mine are accepting volunteers for their vaccine clinics. The shifts are 3 hours in length, and you have the chance of being pulled aside if they have extra doses for whatever reason. So far this has been VERY common. It doesn't look like my county is doing this - not surprising, we're very large so we probably have enough certified hands - but if anyone is antsy about getting it you could check your areas too!

 

[sullivan.kscott]

Update on DW after her Moderna #2. She received it on Thursday evening (1/28) at 6pm. By Friday at 4pm, she was forced to call it a day and lie down. She was able to work from home, so it was easy for her to call the shots. From about 24-48 hours post-injection, she really fought a fever and body aches. Peaked at 102°F, and she did take a few doses of Tylenol and Advil when things got too uncomfortable.

Doing much better today; no fever and a mild headache before breakfast. Everything seems to have subsided now.

 

[Southern Pirate]

I received my 2nd shot last week, the only side effects I felt, other than a sore arm about like a tetanus shot, was a headache. I will be testing for antibodies at the end of the week just because I am curious. Also I read were Port Canaveral does not expect cruise ships until July. Did anyone else see that?

 

[PrincessShmoo]

Also I read were Port Canaveral does not expect cruise ships until July. Did anyone else see that?

Yes. Here's the thread:
https://www.disboards.com/threads/port-canaveral-projecting-no-cruises-until-july.3824442/

 

[brentm77]

I received my 2nd shot last week, the only side effects I felt, other than a sore arm about like a tetanus shot, was a headache. I will be testing for antibodies at the end of the week just because I am curious. Also I read were Port Canaveral does not expect cruise ships until July. Did anyone else see that?

The port budgeted for what it thinks is the "worst-case scenario," which is cruising no later than July. I think many here think that's actually more of a best-case scenario.

 

[0FF TO NEVERLAND]

I have no issue getting the J&J

Yes, it was less effective keeping you from getting Covid, but still VERY good for a vaccine. But it was also 85 percent effective against severe Covid, and 100 percent effective against hospitalization and deaths, and those are the numbers to me that are more important. Very happy and excited about J&J

I know alot of family members who had their vaccines so far, doing well, no side effects thankfully

I just wanna cruise ;]

 

[0FF TO NEVERLAND]

Update on DW after her Moderna #2. She received it on Thursday evening (1/28) at 6pm. By Friday at 4pm, she was forced to call it a day and lie down. She was able to work from home, so it was easy for her to call the shots. From about 24-48 hours post-injection, she really fought a fever and body aches. Peaked at 102°F, and she did take a few doses of Tylenol and Advil when things got too uncomfortable.

Doing much better today; no fever and a mild headache before breakfast. Everything seems to have subsided now.

Thats great. Glad she is feeling better.

On the bright side, that means the body was defending and doing the response of what it's supposed to do. The body is now ready for battle to destroy in the future =]

 

[sullivan.kscott]

Thats great. Glad she is feeling better.

On the bright side, that means the body was defending and doing the response of what it's supposed to do. The body is now ready for battle to destroy in the future =]

Yes, of course! Just being honest in reporting. She’s a little more susceptible to side effects in most things, but with a history of pneumonia and asthma the vaccine was a no-brainer for her. As a nurse with almost 20 years’ trauma and post-CV surgery experience, she was well versed in what to expect .

Here’s to a drink of the day in the near-ish future!

 

[Southern Pirate]

I have no issue getting the J&J

Yes, it was less effective keeping you from getting Covid, but still VERY good for a vaccine. But it was also 85 percent effective against severe Covid, and 100 percent effective against hospitalization and deaths, and those are the numbers to me that are more important. Very happy and excited about J&J

I know alot of family members who had their vaccines so far, doing well, no side effects thankfully

I just wanna cruise ;]

Those are really good numbers especially when you look at what the CDC has come to expect from the flu vaccine. "In the passed 10 years the most effective vaccine was in 2010-11 when it was 60% effective. The least effective was the vaccine from 2014-15 when it was estimated to be only 19% effective." (from the CDC website).

 

[ruadisneyfan2]

So far just feeling mild fatigue. All my itchy spots that were almost gone from shot #1 have been reawakened. Not terribly but I notice I am scratching a lot in those areas. I've never had anything but a sore spot on my arm for past vaccines. While waiting the 15 mins post injection, I massaged the area. I didn't do that the first time and my arm is not sore this time.
The itchy rash that I had last time didn't begin until 4 days later so I know I'm not out of the woods yet.

My fatigue increased last night and was feeling a bit dizzy too so I stayed home from work today. I wonder if part of that is due to dehydration from Saturday. Let's just say my GI tract was um, "overstimulated".

Those are really good numbers especially when you look at what the CDC has come to expect from the flu vaccine. "In the passed 10 years the most effective vaccine was in 2010-11 when it was 60% effective. The least effective was the vaccine from 2014-15 when it was estimated to be only 19% effective." (from the CDC website).

Funny, that you mention this. I was just saying at work last week, since when did we become so critical of a vaccine's efficacy rates & we stop to compare brands ? Most of my coworkers don't even know the name of or manufacturer of the flu shot we received in November. They don't know how many or which strains were included with the vaccine. I looked it up at the time but I don't remember any of it except that there were 4 strains and one of them was H1N1. I can't recall thinking of any of these things when I got my last tetanus shot.
Suddenly, we are accustomed to 95% effective so we're all critcal when it's 70%???

 

[mevelandry]

I'm seeing more and more recommendations from health specialists on tv saying it would be better to abstain from drinking (for a while) following vaccination so the vaccine can be more efficient. Interesting...