Agree with others that if you are limiting it to DS, Boathouse is your best bet. They have a huge menu and tons of seafood options. If you're willing to look outside of the DS springs area, Flying Fish and Narcoossee's are our favorites. The latter has some of the best shrimp pasta and scallop dishes I've ever had. I rarely eat the same dish twice, but the food at Narcoosee's is so good I'm willing to make an exception. Flying fish is top tier too, I just find their menu a little limited.