I'm going to go out on a limb here, and predict that the two rides in Pandora are going to be crazy popular, and FP+ is going to be tiered, so you are likely going to need to get FP+ for one of them, and ride the other standby, which I am going to guess you will need to do at Rope Drop in order to avoid standing in an insanely long line. That will mean that even though the Safari is arguably best at Rope Drop, you are going to find yourself experiencing that a bit later in the day.
I'm also going to venture that with the addition of Pandora, AK is no longer going to be a 5 hour park. I think if you want to experience all, or at least the majority of the rides, you are probably looking at a 7 to 8 hour day.
Without a doubt, AK is the hottest place on the planet. Worse, most of the QS locations have outdoor seating (Flame Tree BBQ, Anandapur Markets), and some of the shows (Flights of Wonder, which is an amazing show, and Rivers of Light) are outside as well. Drink, drink, drink (water that is) and then drink some more, and take it easy on the AK day. The heat and humidity in that park will really take a lot out of you.